Daphne Zuniga made her film debut in a supporting part in the slasher film The Dorm That Dripped Blood (1982), while a student at the University of California, Los Angeles. She was then cast in the 1984 horror film The Initiation (1984), opposite Vera Miles and Clu Gulager. This was followed by a lead role, opposite John Cusack, in Rob Reiner's film, The Sure Thing (1985). In 1986, she starred as Princess Vespa in Mel Brooks' memorable cult comedy Spaceballs (1987), followed by a supporting part in the science fiction horror sequel, The Fly II (1989). From 1992 to 1996, Zuniga portrayed Jo Reynolds on the wildly popular soap opera Melrose Place (1992), which garnered Zuniga wider mainstream exposure. Her role on the series would be followed by numerous appearances on television series, including a lead role as Shelly Pierce on American Dreams (2004) from 2004 to 2005, and a recurring on the popular CW series, One Tree Hill (2003), as Victoria Davis, a role which she played from 2008 until 2012.
*All scheduled events are subject to change